Michael Amling, Prof. Dr. Med, has been Director and Chair of the Department of Osteology and Biomechanics (IOBM), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany since 2010 and Director of the Center for Biomechanics and Skeletal Biology, Hamburg since 2005. He was a postdoctoral associate in cell biology and orthopaedics, Yale University, USA from 1995 to 1997, a resident in orthopedics and trauma surgery, Hamburg University (1997 to 2002), consultant in the Department of Trauma Hand and Reconstructive Surgery, UKE (2002-2004) and professor of experimental trauma surgery, Hamburg University (20024-2009).
He obtained his MD at Hamburg University in 1993, his habilitation in trauma surgery at the same university in 2003 and in 2008 a MBA from the European Business School Oestrich-Winkel, International University Schloss Reichartshausen.
He is the recipient of a number of awards including the von Recklinghausen award 1994‚ the Julius-Wolff award 1996 and 1997, the Dr. Martini award 2001, the Hans-Liniger award 2003 and the Harold-Copp award 2015. He is a member of the National Academy of Science Leopoldina, spokesman of the National Bone Board and Editor of the journal, Bone.
Bone 2020 – genetics and biomechanics
Molecular genetics has become an integral part of routine clinical assessment of patients with bone and joint diseases. This translational molecular approach is of paramount importance as it has led to a better understanding of skeletal physiology and pathophysiology. Moreover, molecular genetics, i.e. the identification of disease-causing mutations in specific genes, provides new insights in how the body senses mechanical signals and transfers them into biological responses. Furthermore, it allows improved diagnostic classification of bone diseases, and has paved the way to developing the first molecular therapies in the bone field. This lecture will highlight some aspects of our current understanding of bone from a clinical perspective.
Aim, Objectives & Learning Outcomes
- Aim: To describe the role of molecular genetics in the assessment of patients with bone and joint diseases.
- Objectives: To provide a contemporary overview of the research in molecular genetics and bone/joint disease and to illustrate the clinical importance.
- Learning outcomes: Following this presentation, attendees should know about the importance of molecular genetics in this field and know the clinical implications for patients affected by bone/ joint disease.